It is pretty clearly established that questions about MATLAB, Macsyma, and other computer algebra systems are on topic. And indeed this page includes "software that mathematicians use" as an on topic subject.
But I think that it was also pretty well established that questions like "how to install MATLAB" or "Where can I download the Maple manual" type of questions are strictly off topic here.
So perhaps we can clarify that in the page linked above? Perhaps by changing the on topic, to specify that the questions about software should be mathematical in nature, and not about programming or general help regarding the software.